Regulatory History: Aspartame
Tracking global safety evaluations, classification changes, and regional status updates for E951.
Factual Regulatory Reference
This database provides factual regulatory information compiled from official government sources. It does not constitute medical, nutritional, or safety advice. Regulatory status varies by country and is subject to change. Always refer to your local regulatory authority for the most current information.
Comprehensive Timeline
Aspartame discovered accidentally by chemist James M. Schlatter while developing anti-ulcer drug.
FDA initially approved aspartame for limited uses, but approval was stayed pending further review.
FDA approved aspartame for dry goods and tabletop sweetener use.
FDA approved aspartame for use in carbonated beverages.
FDA approved aspartame as a general purpose sweetener for all foods and beverages.
EFSA Scientific Committee on Food confirmed safety and ADI of 40 mg/kg bw/day.
EFSA completed comprehensive risk assessment, concluded aspartame and its breakdown products are safe at current exposure levels. Confirmed ADI of 40 mg/kg bw/day.
IARC classified aspartame as 'possibly carcinogenic to humans' (Group 2B) based on limited evidence.
JECFA (meeting same month as IARC) reaffirmed ADI of 0-40 mg/kg bw/day, concluded no reason to change previously established safe intake levels.
WHO and EFSA clarified that aspartame remains safe at current exposure levels despite IARC Group 2B classification. IARC identifies hazard, not risk at typical consumption.