Regulatory History: Tartrazine
Tracking global safety evaluations, classification changes, and regional status updates for E102.
Factual Regulatory Reference
This database provides factual regulatory information compiled from official government sources. It does not constitute medical, nutritional, or safety advice. Regulatory status varies by country and is subject to change. Always refer to your local regulatory authority for the most current information.
Comprehensive Timeline
Tartrazine approved for use in foods in the USA.
Tartrazine listed as certified color additive FD&C Yellow No. 5 under Color Additives Amendment.
FDA required specific labeling of tartrazine due to reports of allergic reactions in sensitive individuals, particularly those with aspirin sensitivity.
Southampton study published in The Lancet suggesting link between artificial colors (including tartrazine) and hyperactivity in children.
EFSA reviewed Southampton study, concluded evidence does not warrant revision of ADI but noted some children may show sensitivity.
EU mandated warning label on foods containing tartrazine and other azo dyes: 'may have an adverse effect on activity and attention in children'.
EFSA re-evaluated tartrazine (E102), reduced ADI from 7.5 to 7.5 mg/kg bw/day after comprehensive review of toxicological data.
California Assembly Bill introduced to ban tartrazine and other synthetic dyes in foods (not enacted).