flavor_enhancer INS 626

Guanylic Acid E626

nucleotide_umami β€” Primarily natural_or_synthetic.

πŸ‡ͺπŸ‡Ί EU: Approved
πŸ‡ΊπŸ‡Έ USA: Approved
πŸ‡―πŸ‡΅ Japan: Approved
πŸ‡¦πŸ‡Ί AU/NZ: Approved
πŸ‡¨πŸ‡¦ Canada: Approved
Scientific Name

Guanosine-5'-monophosphate

CAS: 85-32-5

Data verified: 2026-04-04

Factual Regulatory Reference

This database provides factual regulatory information compiled from official government sources. It does not constitute medical, nutritional, or safety advice. Regulatory status varies by country and is subject to change. Always refer to your local regulatory authority for the most current information.

? Did You Know?

Guanylic Acid occurs naturally in Mushrooms (especially shiitake) and Dried fish. Many people consume it daily without realizing it's also a listed food additive.

Guanylic Acid isn't just a food additive β€” it's also used in medicine.

In the EU, Guanylic Acid has a "quantum satis" authorization β€” Latin for "as much as needed." This means there's no specific maximum limit; manufacturers use only what's technologically necessary.

Detailed Regulatory Assessment

πŸ‡ͺπŸ‡Ί

European Union (EFSA)

approved Max: quantum satis mg/kg

None

Official EFSA Link
πŸ‡ΊπŸ‡Έ

United States (FDA)

approved GRAS

Generally recognized as safe

πŸ‡―πŸ‡΅

Japan (MHLW)

approved Cat: ζ—’ε­˜ζ·»εŠ η‰©

Compliant with Japanese food sanitation law.

Acceptable Daily Intake (ADI)

International Standard (JECFA)

Not specified (ADI not limited)

mg/kg body weight per day

European Standard (EFSA)

Not specified

Everyday Perspective

For a 60kg adult, this limit is roughly equivalent to consuming:

Natural Occurrence

A nucleotide that provides intense umami flavor. Synergistic with glutamates, multiplying umami taste intensity up to 8-fold when combined.

Mushrooms (especially shiitake)Dried fishSeaweedYeast extract

Manufacturing

Method: enzymatic degradation or extraction

Produced by enzymatic degradation of RNA from yeast or fish, or extracted from dried mushrooms.

Applications Beyond Food

Medical

Nutritional supplement, research reagent

Frequently Asked Questions

What is Guanylic Acid (E626)?
Guanylic Acid (E626) is a flavor_enhancer used in food products. It is nucleotide_umami and natural_or_synthetic. A nucleotide that provides intense umami flavor. Synergistic with glutamates, multiplying umami taste intensity up to 8-fold when combined.
Where is Guanylic Acid found naturally?
Guanylic Acid is naturally found in Mushrooms (especially shiitake), Dried fish, Seaweed, Yeast extract. A nucleotide that provides intense umami flavor. Synergistic with glutamates, multiplying umami taste intensity up to 8-fold when combined.
What is the ADI for Guanylic Acid?
The Acceptable Daily Intake (ADI) for Guanylic Acid is Not specified (ADI not limited) as established by JECFA (Joint FAO/WHO Expert Committee on Food Additives). ADI represents the amount that can be consumed daily over a lifetime without appreciable health risk.
What foods contain Guanylic Acid?
Guanylic Acid is used in various food categories including Salts, spices, soups, sauces, salads and protein products. It is used as a flavor_enhancer in these products.
Is Guanylic Acid the same as 5'-GMP?
Yes, Guanylic Acid is also known as 5'-GMP, Guanosine monophosphate. These are different names for the same substance.