Carboxymethyl Cellulose E466
stabilizer, emulsifier, moisture retention agent, viscosity modifier β Primarily natural (modified).
Carboxymethylcellulose sodium salt (CMC)
CAS: 9004-32-4
Factual Regulatory Reference
This database provides factual regulatory information compiled from official government sources. It does not constitute medical, nutritional, or safety advice. Regulatory status varies by country and is subject to change. Always refer to your local regulatory authority for the most current information.
? Did You Know?
Carboxymethyl Cellulose is derived from plant materials β its origin is more natural than its E-number might suggest.
Beyond food, Carboxymethyl Cellulose is also used in cosmetics, medicine, industrial applications, household products. Its versatility makes it one of the most multi-purpose chemical compounds in everyday life.
Although classified as natural in origin, commercial Carboxymethyl Cellulose is typically manufactured rather than extracted directly from food sources.
Detailed Regulatory Assessment
European Union (EFSA)
Widely permitted in most food categories; one of the most commonly used cellulose derivatives.
United States (FDA)
One of most widely used food additives
Japan (MHLW)
Compliant with Japanese food sanitation law.
Acceptable Daily Intake (ADI)
International Standard (JECFA)
mg/kg body weight per day
European Standard (EFSA)
Natural Occurrence
This additive is not known to occur naturally in significant quantities.
Manufacturing
Produced by treating cellulose with alkali (sodium hydroxide), then reacting it with monochloroacetic acid. This substitutes carboxymethyl groups (-OCH2COOH) onto the cellulose backbone. The sodium salt form (sodium carboxymethylcellulose) is highly water-soluble and forms viscous solutions. The degree of substitution determines viscosity and other properties.
Applications Beyond Food
Thickener and stabilizer in toothpaste, lotions, shampoos, and cosmetics.
Tablet binder and disintegrant, ophthalmic lubricant, laxative.
Paper coating, textile sizing, oil drilling fluids, detergents, adhesives.
Toothpaste (most common use - creates smooth texture), laundry detergent, cleaning products.