thickener INS 463

Hydroxypropyl Cellulose E463

emulsifier, stabilizer, film-former, coating agent β€” Primarily natural (modified).

πŸ‡ͺπŸ‡Ί EU: Approved
πŸ‡ΊπŸ‡Έ USA: Approved
πŸ‡―πŸ‡΅ Japan: Approved
πŸ‡¦πŸ‡Ί AU/NZ: Approved
πŸ‡¨πŸ‡¦ Canada: Approved
Scientific Name

Hydroxypropylcellulose

CAS: 9004-64-2

Data verified: 2026-04-04

Factual Regulatory Reference

This database provides factual regulatory information compiled from official government sources. It does not constitute medical, nutritional, or safety advice. Regulatory status varies by country and is subject to change. Always refer to your local regulatory authority for the most current information.

? Did You Know?

Hydroxypropyl Cellulose is derived from plant materials β€” its origin is more natural than its E-number might suggest.

Beyond food, Hydroxypropyl Cellulose is also used in cosmetics, medicine, industrial applications, household products. Its versatility makes it one of the most multi-purpose chemical compounds in everyday life.

Although classified as natural in origin, commercial Hydroxypropyl Cellulose is typically manufactured rather than extracted directly from food sources.

Detailed Regulatory Assessment

πŸ‡ͺπŸ‡Ί

European Union (EFSA)

approved Max: quantum satis mg/kg

Widely permitted in most food categories; considered safe cellulose derivative.

πŸ‡ΊπŸ‡Έ

United States (FDA)

approved GRAS

Regulated as a direct food additive under FDA CFR titles.

πŸ‡―πŸ‡΅

Japan (MHLW)

approved Cat: ζ—’ε­˜ζ·»εŠ η‰©

Compliant with Japanese food sanitation law.

Acceptable Daily Intake (ADI)

International Standard (JECFA)

Not specified (considered inert)

mg/kg body weight per day

European Standard (EFSA)

Not specified

Natural Occurrence

This additive is not known to occur naturally in significant quantities.

Manufacturing

Method: chemical modification

Produced by reacting alkali cellulose with propylene oxide, which adds hydroxypropyl groups to the cellulose backbone. The degree of substitution determines solubility and other properties. HPC is soluble in cold water and many organic solvents.

Applications Beyond Food

Cosmetics

Thickener and film-former in lotions, creams, and hair products.

Medical

Tablet binder and film coating, controlled-release matrix, ophthalmic lubricant (artificial tears).

Industrial

Coatings, ceramics, textiles, construction materials, paper sizing.

Household

Paint additives, ceramic glazes.

Frequently Asked Questions

What is Hydroxypropyl Cellulose (E463)?
Hydroxypropyl Cellulose (E463) is a thickener used in food products. It is emulsifier, stabilizer, film-former, coating agent and natural (modified). Hydroxypropyl cellulose is a semi-synthetic derivative of cellulose, created by chemically modifying natural plant cellulose with propylene oxide. It's processed wood fiber or cotton that's been chemically altered.
What is the ADI for Hydroxypropyl Cellulose?
The Acceptable Daily Intake (ADI) for Hydroxypropyl Cellulose is Not specified (considered inert) as established by JECFA (Joint FAO/WHO Expert Committee on Food Additives). ADI represents the amount that can be consumed daily over a lifetime without appreciable health risk.
What foods contain Hydroxypropyl Cellulose?
Hydroxypropyl Cellulose is used in various food categories including Dairy products and analogues, Confectionery. It is used as a thickener in these products.
Is Hydroxypropyl Cellulose the same as HPC?
Yes, Hydroxypropyl Cellulose is also known as HPC, Cellulose hydroxypropyl ether, Oxypropylated cellulose. These are different names for the same substance.