Beta-cyclodextrin E459
encapsulation agent, carrier, flavor protector β Primarily natural (modified).
Ξ²-Cyclodextrin
CAS: 7585-39-9
Factual Regulatory Reference
This database provides factual regulatory information compiled from official government sources. It does not constitute medical, nutritional, or safety advice. Regulatory status varies by country and is subject to change. Always refer to your local regulatory authority for the most current information.
? Did You Know?
Beyond food, Beta-cyclodextrin is also used in cosmetics, medicine, industrial applications, household products. Its versatility makes it one of the most multi-purpose chemical compounds in everyday life.
Although classified as natural in origin, commercial Beta-cyclodextrin is typically manufactured rather than extracted directly from food sources.
In the EU, Beta-cyclodextrin has a "quantum satis" authorization β Latin for "as much as needed." This means there's no specific maximum limit; manufacturers use only what's technologically necessary.
Detailed Regulatory Assessment
European Union (EFSA)
Approved for use in specified food categories; not widely used in foods compared to pharmaceutical and industrial applications.
United States (FDA)
More commonly used in pharmaceuticals and consumer products than direct food use
Japan (MHLW)
Compliant with Japanese food sanitation law.
Acceptable Daily Intake (ADI)
International Standard (JECFA)
mg/kg body weight per day
European Standard (EFSA)
Natural Occurrence
This additive is not known to occur naturally in significant quantities.
Manufacturing
Produced by enzymatic degradation of starch using cyclodextrin glycosyltransferase (CGTase) enzyme, typically from Bacillus bacteria. The enzyme converts linear starch chains into cyclic structures. Beta-cyclodextrin contains 7 glucose units in a ring, forming a truncated cone shape with a hydrophobic (water-repelling) cavity and hydrophilic (water-loving) exterior. This unique structure allows it to encapsulate guest molecules.
Applications Beyond Food
Stabilizer and odor absorber in cosmetics and personal care products.
Drug delivery system, solubility enhancer, stabilizer for sensitive active ingredients.
Odor control (Febreze uses beta-cyclodextrin to trap odor molecules), textile treatment, pharmaceutical excipient.
Febreze and other odor eliminators (traps odor molecules in molecular cage), air fresheners.