Diphosphates E450
sequestrant, acidity regulator, raising agent — Primarily synthetic.
Disodium diphosphate (E450i), Trisodium diphosphate (E450ii), Tetrasodium diphosphate (E450iii), Dipotassium diphosphate (E450v), Dicalcium diphosphate (E450vii)
CAS: 7758-16-9 (i), 7558-79-4 (ii), 10124-56-8 (iii), 7722-88-5 (v), 68915-31-1 (vii)
Factual Regulatory Reference
This database provides factual regulatory information compiled from official government sources. It does not constitute medical, nutritional, or safety advice. Regulatory status varies by country and is subject to change. Always refer to your local regulatory authority for the most current information.
? Did You Know?
Beyond food, Diphosphates is also used in cosmetics, medicine, industrial applications, household products. Its versatility makes it one of the most multi-purpose chemical compounds in everyday life.
Detailed Regulatory Assessment
European Union (EFSA)
Quantum satis in many categories; specific limits apply due to concerns about total dietary phosphate intake.
Official EFSA LinkUnited States (FDA)
Widely used in processed cheese and baking powder
Japan (MHLW)
Compliant with Japanese food sanitation law.
Acceptable Daily Intake (ADI)
International Standard (JECFA)
mg/kg body weight per day
European Standard (EFSA)
Natural Occurrence
This additive is not known to occur naturally in significant quantities.
Manufacturing
Produced by heating orthophosphates (monophosphates) to high temperatures (above 200°C), causing dehydration and condensation to form diphosphates (pyrophosphates). Different cation forms (sodium, potassium, calcium) are obtained by using the corresponding orthophosphate salts as starting materials.
Applications Beyond Food
Buffering agent and chelating agent in toothpaste and dental products.
Buffering agent in pharmaceutical formulations.
Water treatment, metal surface treatment, detergents, textile processing.
Toothpaste (tetrasodium pyrophosphate prevents tartar), cleaning products, baking powder.