Glycerol E422
polyol β Primarily natural/synthetic.
1,2,3-Propanetriol
CAS: 56-81-5
Factual Regulatory Reference
This database provides factual regulatory information compiled from official government sources. It does not constitute medical, nutritional, or safety advice. Regulatory status varies by country and is subject to change. Always refer to your local regulatory authority for the most current information.
? Did You Know?
Glycerol occurs naturally in all fats and oils (as triglyceride backbone) and all living cells. Many people consume it daily without realizing it's also a listed food additive.
Glycerol is derived from plant materials β its origin is more natural than its E-number might suggest.
Beyond food, Glycerol is also used in cosmetics, medicine, industrial applications, household products. Its versatility makes it one of the most multi-purpose chemical compounds in everyday life.
Detailed Regulatory Assessment
European Union (EFSA)
Widely permitted in most food categories with no upper limit
United States (FDA)
Generally recognized as one of the safest food additives
Japan (MHLW)
Compliant with Japanese food sanitation law.
Acceptable Daily Intake (ADI)
International Standard (JECFA)
mg/kg body weight per day
European Standard (EFSA)
Natural Occurrence
Glycerol forms the backbone of all fats and oils (triglycerides) in nature. It is found in every living cell and is released naturally during the saponification process in soap-making.
Manufacturing
Modern glycerol is primarily produced as a byproduct of biodiesel and soap production from vegetable oils (soy, palm, coconut). Can also be synthesized from petrochemical propylene, or derived from animal fats (less common today). Most commercial glycerol is now plant-based.
Applications Beyond Food
Extensively used in skincare, lotions, creams, toothpaste, and mouthwash as a moisturizer and humectant.
Common in suppositories, cough syrups, ear drops, and as a vehicle for medications.
Used in antifreeze, de-icing fluids, and as a precursor for explosives (nitroglycerin/dynamite).
Found in e-cigarette liquid, personal lubricants, and food preservation.