Dodecyl Gallate E312
synthetic phenolic antioxidant — Primarily synthetic.
Dodecyl 3,4,5-trihydroxybenzoate
CAS: 1166-52-5
Factual Regulatory Reference
This database provides factual regulatory information compiled from official government sources. It does not constitute medical, nutritional, or safety advice. Regulatory status varies by country and is subject to change. Always refer to your local regulatory authority for the most current information.
? Did You Know?
Beyond food, Dodecyl Gallate is also used in cosmetics, medicine, industrial applications. Its versatility makes it one of the most multi-purpose chemical compounds in everyday life.
Regulatory opinions differ: Dodecyl Gallate is approved in USA, JAPAN, CANADA but banned in EU. This reflects different risk assessment philosophies between regions.
Detailed Regulatory Assessment
European Union (EFSA)
REMOVED from EU approved additives list in 2018 due to persistent safety concerns
United States (FDA)
Previously approved with limits; current use declining after EU removal
Japan (MHLW)
Status maintained despite EU removal
Acceptable Daily Intake (ADI)
International Standard (JECFA)
mg/kg body weight per day
European Standard (EFSA)
Everyday Perspective
For a 60kg adult, this limit is roughly equivalent to consuming:
Natural Occurrence
This additive is not known to occur naturally in significant quantities.
Manufacturing
Produced by esterifying gallic acid with dodecanol (dodecyl/lauryl alcohol). Highest fat solubility of all gallates due to 12-carbon chain. Empirical formula: C₁₉H₃₀O₅, Molecular weight: 338.44.
Applications Beyond Food
Historical use in cosmetics and hair products (now largely discontinued)
Historical use (discontinued)
Limited to research/analytical standards